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Similar effects on hypertension were being observed with 25 mg, 50 mg and 100 mg of VIAGRA, therefore the effects are usually not relevant to dose or plasma stages inside this dosage vary. Much larger results ended up recorded amid sufferers receiving concomitant nitrates [see CONTRAINDICATIONS].

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The next gatherings happened in < two% of patients in controlled clinical trials; a causal connection to VIAGRA is uncertain. Described activities include All those using a plausible relation to drug use; omitted are insignificant gatherings and reviews too imprecise to be meaningful:

Medicines are sometimes prescribed for needs other than All those shown within a Affected person Facts leaflet. Do not use VIAGRA for any affliction for which it wasn't prescribed. Never give VIAGRA to other people, even though they have got exactly the same indicators you have. It may hurt them.

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Consequences of Other Medicine on VIAGRA Sildenafil metabolism is principally mediated by CYP3A4 (key route) and CYP2C9 (slight route). Consequently, inhibitors of these isoenzymes may perhaps lessen sildenafil clearance and inducers of these isoenzymes may maximize sildenafil clearance.

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The indicate profiles of the modify from baseline in standing systolic hypertension in subjects addressed with doxazosin together with 50 mg VIAGRA or matching placebo are demonstrated in Determine 3.

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